Hematocrit Changes as Parameters for Giving Mannitol in Severe Head Injury

Treatment for severe head injury.

Difficulties in establishing the value of certain treatments for head injury are reviewed. An analysis of 1000 severely head injured patients, managed by varying methods in three different countries, showed that certain treatments were more often used in the most severely injured patients. Even when the severity of injury was taken account of, it appeared that the use of steroids and tracheosto...

Patient after Severe Head Injury

Background: The pharmacodynamic differences in time to onset and dissipation of effect of sufentanil, fentanyl, and alfentanil probably result from different rates of blood-brain equilibration. The authors investigated this hypothesis in humans. Methods: After simultaneous central venous bolus application of sufentanil (10 pg), fentanyl (100 pg), and alfentanil (1,000 pg), arterial and jugular ...

Neuroprotective agents in severe head injury.

Running head : Gift Giving in Courtship Gift Giving as Costly Signaling in Courtship Contexts

Social scientists from a variety of fields have grappled with questions about why gift giving exists and where its utility comes from because it is economically inefficient. Economic models of sexual relationships (e.g., Baumeister & Vohs, 2004) propose that gifts given by men are motivated by attempts to barter for access to sex. We offer an alternative model, based on costly signaling theory ...

Mannitol for resuscitation in acute head injury: effects on cerebral perfusion and osmolality.

OBJECTIVE To review the use of mannitol during initial resuscitation following traumatic brain injury and to determine the effects of mannitol on subsequent management following resuscitation and commencement of neuromonitoring. METHODS A retrospective audit of patients presenting to a tertiary hospital with severe head injury (Glasgow coma score < or = 8). Patients were divided into two grou...